2 results for "GPBA Receptor Agonists" in 产品

GPBA Receptor Agonists

GPBA receptors (GPBAR1, M-BAR, TGR5) are G protein-coupled receptors (GPCRs) that are activated by bile acids. They are primarily expressed in the gallbladder, ileum and colon, and are important in the regulation of glucose and lipid metabolism, and energy expenditure.

GPBA receptors are members of the class A (rhodopsin-like) subgroup of GPCRs and are present at varying levels in the liver, gallbladder, ileum, colon, heart, spleen, kidney, placenta, leukocytes, skeletal muscle, brown adipose ...

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GPBA receptor (TGR5) agonist

Chemical Name: 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one
Purity: ≥98%
GPBA receptor (TGR5) agonist
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Potent and selective GPBA receptor (TGR5) agonist

Chemical Name: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
Purity: ≥98%
Potent and selective GPBA receptor (TGR5) agonist
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