GPR137B Proteins and Enzymes

TM7SF1 is an Orphan-U GPCR with an unknown ligand. This receptor has been shown to be upregulated during kidney development. TM7SF1 has been reported to be expressed in adult kidney and heart, but not in fetal kidney. ESTs have been isolated from a wide variety of tissues, including B-cell/lung/testis, brain, connective tissue, ear, embryo, eye, gall bladder, kidney, liver/spleen, lung, melanocyte/uterus/fetal heart, nerve, pineal, placenta, skin, spleen, testis, tonsil, and vessel libraries.