H+-ATPase Activators

H⁺-ATPase (also known as vacuolar ATPase, V-ATPase) is an enzyme transporter that functions to acidify intracellular compartments in eukaryotic cells. It is ubiquitously expressed and is present in endomembrane organelles such as vacuoles, lysosomes , the Golgi apparatus, chromaffin granules and coated vesicles, as well as in the plasma membrane.

H⁺-ATPase is a multisubunit complex composed of two domains. The V1 domain is responsible for ATP hydrolysis and the V0 domain is responsible for ...