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1 result for "Haspin Inhibitors Small Molecules and Peptides" in 产品
Haspin Inhibitors Small Molecules and Peptides
Haspin (histone H3 associated protein kinase), EC 2.7.11.1, is a serine/threonine kinase that has a critical function in mitosis. The enzyme is localized to chromosomes and phosphorylates threonine-3 on histone H3 during mitosis. Phosphorylation of T3 opens up a binding site for the chromosomal passenger complex and activates Aurora B kinase at the centromere. This enables proper chromatid cohesion and metaphase alignment, ensuring normal progression through the cell cycle.
Haspin is a ...
Potent and selective haspin inhibitor
| Chemical Name: | 3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine trifluoroacetate |
| Purity: | ≥98% |
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