8 results for "Histamine H1 Receptor Antagonists" in 产品
Histamine H1 Receptor Antagonists
Histamine H1R (HRH1) is a G-protein coupled 7-transmembrane putative glycoprotein that is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues.
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
| Chemical Name: | α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol |
| Purity: | ≥98% |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% |
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
| Alternate Names: | Hismanal |
| Chemical Name: | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine |
| Purity: | ≥98% |
H1 antagonist
| Chemical Name: | (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl-2-pyrrolidine fumarate |
| Purity: | ≥98% |
H1 antagonist
| Alternate Names: | DPH |
| Chemical Name: | 2-Diphenylmethoxy-N,N-dimethylethanamine hydrochloride |
| Purity: | ≥98% |
H1 antagonist; ocular antiallergic agent
| Chemical Name: | (Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid hydrochloride |
| Purity: | ≥98% |
Selective M2 antagonist
| Chemical Name: | N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate |
| Purity: | ≥98% |
Human pregnane X receptor agonist; H1 antagonist
| Alternate Names: | Meclozine |
| Chemical Name: | 1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride |
| Purity: | ≥99% |
