7 results for "Histone Deacetylase Inhibitors" in 产品
Histone Deacetylase Inhibitors
There are 18 Histone deacetylases (HDAC) enzymes that are classified in to two families, the histone deacetylase family and the sirtuin family. The histone deacetylase family is further divided in to class I (HDACs 1/2/3 and 8), class II (HDACs 4/5/6/7/9/10) and class IV (HDAC 11). The sirtuin family are all classified as class III HDACs. HDACs catalyze acetyl group removal from lysine residues in histones and non-histone proteins, causing transcriptional repression. In general, they do not act ...
PARP-1 inhibitor
| Chemical Name: | Pyridine-3-carboxamide |
| Purity: | ≥99% |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥98% |
Potent and selective class IIa HDAC inhibitor; brain penetrant
| Chemical Name: | 2-(2-Fluorophenyl)-N-hydroxy-2-(4-(5-(trifluoromethyl)pyrimidin-2-yl)phenyl)acetamide |
| Purity: | ≥98% |
Highly potent and selective HDAC2 inhibitor
| Chemical Name: | Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate |
| Purity: | ≥98% |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% |
Selective HDAC11 inhibitor
| Chemical Name: | N'-Hexadecylthiophene-2-carbohydrazide |
| Purity: | ≥95% |
Potent pan-HDAC inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Purity: | ≥98% |
