4 results for "LXR alpha/NR1H3 Small Molecules and Peptides" in 产品
LXR alpha/NR1H3 Small Molecules and Peptides
Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver, whereas the beta isoform expression has been shown to be ubiquitous.
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Potent liver X receptor (LXR) agonist; also CAR inverse agonist
| Chemical Name: | N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]benzenesulfonamide |
| Purity: | ≥98% |
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Orally active liver X receptor (LXR) agonist
| Chemical Name: | 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride |
| Purity: | ≥98% |
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Potent LXR antagonist
| Chemical Name: | 2,4,6-Trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]benzenesulfonamide |
| Purity: | ≥98% |
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Potent LXR agonist
| Chemical Name: | 2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole |
| Purity: | ≥98% |
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