179 results for "Mcl-1" in 产品

Mcl-1 Products

Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is regulated by polyubiquitination, which targets Mcl-1L to the proteasome pathway.

Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, IP
Western Blot: Mcl-1 Antibody [NB100-56146]
(3)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL1128
Applications: IHC, WB, ICC/IF
Western Blot: Mcl-1 Antibody (CL1128) [NBP2-52968]
(7)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #SI16-04
Applications: IHC, WB, Flow, ICC/IF, IP
Western Blot: Mcl-1 Antibody (SI16-04) [NBP2-67400]
(11)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #OTI10F6
Applications: IHC, WB, Flow, ICC/IF
Western Blot: Mcl-1 Antibody (OTI10F6) [NBP2-45773]
(10)
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat, Canine, Feline
Details: Rabbit IgG Monoclonal Clone #HL1544
Applications: IHC, WB
Mcl-1 Antibody (HL1544) - Azide and BSA Free
(7)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL1128
Applications: IHC, WB, ICC/IF
Mcl-1 Antibody (CL1128) - Azide and BSA Free Immunohistochemistry-Paraffin: Mcl-1 Antibody [NBP3-43898]
(7)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #OTI10F6
Applications: IHC, WB, Flow, ICC/IF, CyTOF-ready
Western Blot: Mcl-1 Antibody (OTI10F6)Azide and BSA Free [NBP2-72598]
(4)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #8C6
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: Mcl-1 Antibody (8C6)BSA Free [NB100-2194]
(3)
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Reactivity: Human
Source: Sf 21 (baculovirus)
Applications: WB
R&D Systems Recombinant Proteins and Enzymes
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Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation

Alternate Names: Filanesib
Chemical Name: (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate
Purity: ≥98%
Potent and selective kinesin spindle protein (KSP) inhibitor; induces Mcl-1 degradation
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Inhibitor of Bcl-2 family members; antiapoptotic

Alternate Names: GX15-070
Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
Purity: ≥98%
Inhibitor of Bcl-2 family members; antiapoptotic
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Recombinant Monoclonal Antibody

Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #S04-3A4
Applications: WB, ICC/IF
Western Blot: Mcl-1 Antibody (S04-3A4) [NBP3-19546]
(2)
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Reactivity: Human
Applications: AC
Mcl-1 Antibody Blocking Peptide
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Reactivity: Human
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