mGluR1 Proteins and Enzymes

Metabotropic glutamate receptor 1 (mGluR1) is a 130 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. On neurons, mGluR1 is postsynaptic, associates with G_q-like proteins, mobilizes intracellular Ca⁺⁺, and influences ion channel activity. Mature mGluR1 is 1176 amino acids...