MYC Inhibitors Small Molecules and Peptides

MYC (Myc proto-oncogene protein) is a nuclear protein that acts as a transcription factor, driving cell growth, self-renewal, proliferation and differentiation under normal conditions. MYC belongs to a family of transcription factors that includes N-Myc and L-Myc, and is a subgroup of the larger class of bHLHZ (basic-helix loop-helix leucine zipper domain) transcription factors. MYC heterodimerizes with MAX, enabling DNA binding and transcriptional regulation. MYC is the endpoint for numerous ...