Neuromedin BR/NMBR CDNA Clones

NMBR (neuromedin-B receptor) is an 80 kDa, 390 amino acid (aa) G-protein coupled 7-transmembrane glycoprotein receptor for bombesin-like peptides, binding NMB with high affinity and GRP (gastrin releasing peptide) with lower affinity. NMBR expression in the olfactory and central thalamic regions of the brain plays a role in thermoregulation. It has also been shown to be mitogenic in colonic epithelium. Expression in the pituitary gland is important for regulation of the pituitary-thyroid axis.