6 results for "Nicotinic (a7) Receptor Modulators Small Molecules and Peptides" in 产品
Nicotinic (a7) Receptor Modulators Small Molecules and Peptides
α7 is a subunit of the neuronal nicotinic receptor that can combine to form homomeric receptors. In avian tissue α7α8 heteromers also occur and an association between α7 and β2 subunits has been suggested in the mammalian brain. The α7 nAChR is particularly prominent in the hippocampus, where it is found on GABAergic interneurons of stratum oriens and stratum radiatum, and on pyramidal neurones.
Presynaptic α7 nAChRs are present on glutamate terminals and ...
Positive allosteric modulator of α7 nAChRs; active in vivo
| Chemical Name: | N-(5-Chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% |
Positive allosteric modulator of α7 nAChRs; active in vivo
| Chemical Name: | N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea |
| Purity: | ≥98% |
Positive allosteric modulator of α7 nAChRs
| Alternate Names: | XY 4083 |
| Chemical Name: | [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide |
Allosteric potentiator of α7, α4β2 and α4β4 nAChRs
| Chemical Name: | [2-[(4-Fluorophenyl)amino]-4-methyl-5-thiazolyl]-3-thienylmethanone |
| Purity: | ≥98% |
Positive allosteric modulator of α7 nAChRs
| Chemical Name: | 4-[5-(4-Chlorophenyl)-2-methyl-3-(1-oxopropyl)-1H-pyrrol-1-yl]benzenesulfonamide |
| Purity: | ≥97% |
Positive allosteric modulator of α7 nAChRs; analgesic
| Alternate Names: | (-)-(S)-B 973B |
| Chemical Name: | 3,4-Difluoro-N-[(1S)-1-[6-[4-(2-pyridinyl)-1-piperazinyl]-2-pyrazinyl]ethyl]benzenepropanamide |
| Purity: | ≥98% |
