Nitric Oxide Small Molecules and Peptides

Nitric Oxide (NO) is a gaseous free radical with a short half-life in vivo of a few seconds or less. It is a pleiotropic biological mediator that regulates diverse activities ranging from neuronal function to immune system regulation. NO is catalyzed by enzymes of the Nitric Oxide Synthase (NOS) family, which include neuronal NOS (nNOS/NOS1), inducible NOS (iNOS/NOS2), and endothelial NOS (eNOS/NOS3). NO is lipid soluble, so it is not stored by synthesized de novo and freely diffuses across ...