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3 results for "NOP Receptor Antagonists Small Molecules and Peptides" in 产品
NOP Receptor Antagonists Small Molecules and Peptides
The NOP receptor, (also known as ORL1, N/OFQ receptor), is a member of the opioid family of G-protein-coupled receptors that also includes κ, δ and μ receptors. NOP receptor mRNA is found in high levels in the cortex, anterior olfactory nucleus, lateral septum, hypothalamus, hippocampus, amygdala, central grey, pontine nuclei, interpeduncular nucleus, substantia nigra, raphe complex, locus coeruleus and spinal cord.
The pattern of NOP receptor distribution suggests the ...
Potent and selective NOP antagonist
| Chemical Name: | (±)-1-[(3R*,4R*)-1-(Cyclooctylmethyl)-3-(hydroxymethyl)-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Purity: | ≥98% |
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Selective NOP antagonist
| Chemical Name: | (5S,7S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol hydrochloride |
| Purity: | ≥97% |
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Selective NOP antagonist
| Chemical Name: | N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide hydrochloride |
| Purity: | ≥98% |
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