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2 results for "Orexin Receptor Antagonists" in 产品
Orexin Receptor Antagonists
Hypocretin receptor 2 (HCRTR2); also known as orexin receptor 2 or OX2R is a 40 kDa 7-transmembrane G-protein-coupled glycoprotein that is a high affinity receptor for orexins A and B (hypocretins 1 and 2). In mouse brain, engagement of HCRTRs promotes wakefulness, such that absence of either orexins or their receptors creates a narcolepsy-like sta...
Potent, dual orexin receptor antagonist
| Chemical Name: | N-[1,1'-Biphenyl]-2-yl-1-[2-[(1-methyl-1H-benzimidazol-2-yl)thio]acetyl-2-pyrrolidinedicarboxamide |
| Purity: | ≥98% |
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Potent, dual orexin receptor antagonist
| Chemical Name: | (2S)-N-(3,5-Dimethylphenyl)-1-[(4-methoxyphenyl)sulfonyl]-2-pyrrolidinecarboxamide |
| Purity: | ≥98% |
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