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3 results for "OX2 Receptor Antagonists" in 产品
OX2 Receptor Antagonists
The OX2 receptors, also known as hypocretin receptor 2, are located primarily in the cerebral cortex, paraventricular hypothalamus, nucleus accumbens, subthalamic and paraventricular thalamus where they are thought to regulate sleep-wakefulness. The OX2 receptor displays equal affinity for Orexin A and Orexin B. The human OX2 receptor gene has been localized to chromosome 6 (6p11-q11).
Potent and selective OX2 antagonist
| Chemical Name: | (2S)-1-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-[(4-pyridinylmethyl)amino]-1-butanone hydrochloride |
| Purity: | ≥98% |
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Selective OX2 antagonist
| Chemical Name: | N-(2,4-Dibromophenyl)-N'-[(4S,5S)-2,2-dimethyl-4-phenyl-1,3-dioxan-5-yl]-urea |
| Purity: | ≥98% |
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Highly potent and selective OX2 antagonist; brain penetrant
| Chemical Name: | N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide |
| Purity: | ≥98% |
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