Oxytocin Receptor Agonists

Oxytocin receptors (OT) are G-protein-coupled receptors that mediate parturition and lactation. They are closely related to vasopressin receptors. Oxytocin receptors are coupled to G_q/11 proteins and are localized to the myoepithelial cells of the mammary gland, and are also expressed in the myometrium and endometrium of the uterus at the end of pregnancy.

Oxytocin receptors are involved in smooth muscle contraction of the uterus during parturition and facilitate lactation. These receptors ...