4 results for "PAI-1 Inhibitors Small Molecules and Peptides" in 产品
PAI-1 Inhibitors Small Molecules and Peptides
Plasminogen activator inhibitor-1 (PAI-1) is a serine protease inhibitor, encoded by the SERPINE1 gene. High levels of this protein are a risk factor for thrombosis and atherosclerosis, and elevated blood levels are associated with poor clinical outcome and response to therapy in cancer patients.
PAI-1 is the primary regulator of the plasminogen activation system, through its inhibitory action on tissue plasminogen activator (tPA) and urokinase (uPA). Both tPA and uPA cleave plasminogen to ...
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
| Chemical Name: | 2-[5-[[6-[5-(1,1-Dimethylethyl)-2-benzoxazolyl]-2-naphthalenyl]oxy]pentyl]propanedioic acid disodium salt |
| Purity: | ≥98% |
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
| Chemical Name: | 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
| Purity: | ≥98% |
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
| Alternate Names: | PAI 039,tiplasinin |
| Chemical Name: | α-Oxo-1-(phenylmethyl)-5-[4-(trifluoromethoxy)phenyl]-1H-indole-3-acetic acid |
| Purity: | ≥98% |
Plasminogen activator inhibitor-1 (PAI-1) inhibitor; orally bioavailable
| Chemical Name: | 5-Chloro-2-[[2-[2-[4-(Diphenylmethyl)-1-piperazinyl]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt |
| Purity: | ≥98% |