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108 results for "PAK4" in 产品
PAK4 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
![Western Blot: PAK4 Antibody (OTI1C7) [NBP2-46316]](https://resources.rndsystems.com/images/products/PAK4-Antibody-1C7-Western-Blot-NBP2-46316-img0013.jpg "Western Blot: PAK4 Antibody (OTI1C7) [NBP2-46316]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
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Potent PAK inhibitor; brain penetrant and orally bioavailable
| Chemical Name: | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
| Purity: | ≥98% |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PAK4 AntibodyBSA Free [NBP1-77236]](https://resources.rndsystems.com/images/products/PAK4-Antibody-Western-Blot-NBP1-77236-img0001.jpg "Western Blot: PAK4 AntibodyBSA Free [NBP1-77236]")
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, Mycoplasma |
![Western Blot: PAK4 Antibody [NBP2-58833]](https://resources.rndsystems.com/images/products/PAK4-Antibody-Western-Blot-NBP2-58833-img0003.jpg "Western Blot: PAK4 Antibody [NBP2-58833]")
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, Mycoplasma |
![Western Blot: PAK4 Antibody [NBP2-56634]](https://resources.rndsystems.com/images/products/PAK4-Antibody-Western-Blot-NBP2-56634-img0003.jpg "Western Blot: PAK4 Antibody [NBP2-56634]")
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Potent PAK4 inhibitor; orally available
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[(2-methylthieno[3,2-d]pyrimidin-4-yl)amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide dihydrochloride |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1C7 |
| Applications: | IHC, WB |
![Western Blot: PAK4 Antibody (OTI1C7)Azide and BSA Free [NBP2-73231]](https://resources.rndsystems.com/images/products/PAK4-Antibody-OTI1C7-Azide-and-BSA-Free-Western-Blot-NBP2-73231-img0001.jpg "Western Blot: PAK4 Antibody (OTI1C7)Azide and BSA Free [NBP2-73231]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBL1-14080]](https://resources.rndsystems.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14080-img0002.jpg "Western Blot: PAK4 Overexpression Lysate [NBL1-14080]")
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| Reactivity: | Human |
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBL1-14081]](https://resources.rndsystems.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14081-img0002.jpg "Western Blot: PAK4 Overexpression Lysate [NBL1-14081]")
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| Reactivity: | Human |
| Applications: | WB |
![Western Blot: PAK4 Overexpression Lysate [NBP2-09153]](https://resources.rndsystems.com/images/products/PAK4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-09153-img0001.jpg "Western Blot: PAK4 Overexpression Lysate [NBP2-09153]")
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| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #3F10 |
| Applications: | WB, ELISA |
![Western Blot: PAK4 Antibody (3F10) [H00010298-M01]](https://resources.rndsystems.com/images/products/PAK4-Antibody-3F10-Western-Blot-H00010298-M01-img0001.jpg "Western Blot: PAK4 Antibody (3F10) [H00010298-M01]")
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| Reactivity: | Human |
| Sensitivity: | 0.1 ng/ml (example only; lot dependent) |
| Assay Range: | 0.313 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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| Reactivity: | Human |
| Source: | E. coli |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human PAK4 His Protein [NBC1-18517]](https://resources.rndsystems.com/images/products/PAK4-Protein-SDS-Page-NBC1-18517-img0001.jpg "SDS-PAGE: Recombinant Human PAK4 His Protein [NBC1-18517]")
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| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
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| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
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