PDGF-A Proteins and Enzymes

Platelet-derived growth factor A (PDGF-A) is a widely expressed cytokine that can form disulfide-linked homodimers or heterodimers with PDGF-B. These proteins regulate diverse cellular functions by binding to and inducing the homo- or hetero-dimerization of PDGF R alpha and R beta. PDGF-AA binds to alpha receptor homodimers, while PDGF-AB additiona...