PGEA1 Proteins and Enzymes

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The proteinencoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenicbeta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin.Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)