Photoswitchable Ligands Small Molecules and Peptides

Photoswitchable ligands are photo-sensitive compounds that can allow the optical regulation of neuronal ion channels and receptors in response to different wavelengths of light. These photoswitches enable a high degree of spatial and temporal control over neuronal signaling, which is usually not possible with conventional pharmacological agents. Furthermore they offer the advantage of being reversible, meaning they can toggle between their cis and trans conformations, as well as being effective ...