RNF43 Proteins and Enzymes

RNF43 (RING finger protein 43) is an E3 ubiquitin ligase that may be expressed on the plasma membrane or intracellularly. It can associate with the nuclear matrix protein HAP95/AKAP8L, the ubiquitin ligase NEDL1, and p53. It also interacts with the cell surface ubiquitin ligase ZNRF3, and both RNF43 and ZNRF3 antagonize Wnt signaling by promoting t...