ROBO1 Lysates

ROBO1 is an axon guidance molecule that is expressed on pioneer axons in the neural tube and proliferative zones of the cortical plate. It plays an important role in axon pathfinding and tract development as well as in neuronal proliferation and dendrite branching. It is restricted to axonal growth cones that do not cross the midline and to midline-crossing axons only after they cross. ROBO1 binds to Slit1 and Slit2, leading to growth cone collapse and axonal branching. It also regulates ...