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sFRP-1 Small Molecules and Peptides

sFRP-1 (Secreted Frizzled Related Protein-1), also known as SARP-2, FRP, and FrzA, is a secreted protein that binds to Wnt-1, -2, -3a, and -4 and prevents their activation of canonical beta-Catenin signaling. sFRP-1 is upregulated in the ischemic heart where it limits inflammation and the severity of tissue damage following myocardial infarction. D...

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Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling

Chemical Name: 5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride
Purity: ≥98%
Secreted Frizzled-related protein-1 (sFRP-1) inhibitor; increases Wnt signaling
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