4 results for "Small G Protein Activators" in 产品
Small G Protein Activators
Like Gα proteins, small GTPases alternate between an 'on' state (bound to GTP) and an 'off' state (bound to GDP) and so function as binary switches that regulate cytosolic signaling pathways. GDP/GTP cycling is controlled by two types of regulatory proteins that associate with small GTPases. Guanine exchange factors (GEFs) promote the formation of the active, GTP bound form of RAS proteins while GTPase activating proteins (GAPs) accelerate GTPase activity, promoting the inactive, GDP bound form.
Selective Epac activator
| Chemical Name: | 8-(4-Chlorophenylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate sodium salt |
| Purity: | ≥99% |
Selective Epac activator; cell-permeable analog of 8CPT-2Me-cAMP (Cat. No. 1645)
| Alternate Names: | 007-AM |
| Chemical Name: | 8-(4-Chlorophenylthio)-2'-O-methyladenosine-3',5'-cyclic monophosphate acetoxymethyl ester |
| Purity: | ≥97% |
cGMP analog; activates PKG
| Chemical Name: | 8-Bromoguanosine cyclic 3',5'-monophosphate sodium salt |
| Purity: | ≥98% |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name: | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity: | ≥98% |
