Having trouble trying to find the right product? Chat with our scientists below - we're here to help!

52 results for "Smoothened" in 产品

Sort by:

Smoothened Products

Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas. Smoothened expression has been documented in bladder, blood, brain, the central nervous system, skin, and ureter. ESTs have been isolated from amnion, bone, brain, breast, embryo, eye, heart, nerve, and skin libraries.

Cyclopamine

Catalog #: 1623

(1)

Chemical Name:	(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Purity:	≥97%

Reactivity:	Human
Details:	Mouse IgG_2A Monoclonal Clone #1015418
Applications:	IHC

Reactivity:	Human, Mouse, Rat, Porcine, Bat, +6 More
Details:	Rabbit IgG Polyclonal
Applications:	IHC, ICC/IF

Chemical Name:	3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride
Purity:	≥98%

Reactivity:	Human, Mouse, Rat
Details:	Rabbit IgG Polyclonal
Applications:	IHC, WB, ELISA

Chemical Name:	1-[4-(5'-Chloro-3,5-dimethyl[2,4'-bipyridin]-2'-yl-1-piperazinyl]-3-(methylsulfonyl)-1-propanone hydrochloride
Purity:	≥98%

Chemical Name:	N,N'-1,4-Phenylenebis[2,5-dichlorobenzamide]
Purity:	≥98%

Chemical Name:	4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
Purity:	≥98%

Alternate Names:	glasdegib,PF-913
Chemical Name:	1-((2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methylpiperidin-4-yl)-3-(4-cyanophenyl)urea maleate salt
Purity:	≥98%

Chemical Name:	rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide
Purity:	≥98%

Reactivity:	Human
Source:	Wheat germ
Applications:	WB, ELISA, AP, MA, PAGE

Reactivity:	Human
Source:	Wheat germ
Applications:	WB, ELISA, AP, MA

Reactivity:	Human
Source:	Wheat germ
Applications:	AP

Smoothened Products

Cyclopamine

Human Smoothened Antibody

Smoothened Antibody - BSA Free

SAG dihydrochloride

Smoothened Antibody - BSA Free

PF 5274857 hydrochloride

IHR 1

Itraconazole

PF 04449913 maleate

Human Smoothened (NP_005622) VersaClone cDNA

Sonidegib

Recombinant Human Smoothened GST (N-Term) Protein

Recombinant Human Smoothened GST (N-Term) Protein

Human Smoothened Alexa Fluor® 488‑conjugated Antibody

Human Smoothened Alexa Fluor® 700‑conjugated Antibody

Human Smoothened Alexa Fluor® 647‑conjugated Antibody

Human Smoothened Alexa Fluor® 750‑conjugated Antibody

Human Smoothened Alexa Fluor® 594‑conjugated Antibody

Human Smoothened Alexa Fluor® 350‑conjugated Antibody

Human Smoothened Alexa Fluor® 405‑conjugated Antibody

Human Smoothened Alexa Fluor® 532‑conjugated Antibody

Smoothened Overexpression Lysate

Smoothened Antibody - BSA Free

Smoothened Antibody - BSA Free

Recombinant Human Smoothened Protein