SPOC1/PHF13 Proteins and Enzymes

The PHF13 gene encodes a 300 amino acid long, 33 kDA PHD finger protein 13 that functions in chromatin structure. It is critical for the condensation of normal chromosome during the preliminary stages of mitosis. Additionally, PHF13 must be used to achieve normal chromosome separation during mitosis. The PHF13 gene interacts with genes RORC, GLTPD1, and KLHL21. It has been linked to ovarian cancer.