SREB3 Proteins and Enzymes

SREB3, a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, is an Orphan-A GPCR with an unknown ligand. SREB3 has been reported to be expressed in several areas of human and rat CNS (Matsumoto et al., 2000), as well as in genital organs. ESTs have been isolated from lung libraries, as well as cancer libraries of the brain, colon, and lung.