8 results for "STING/TMEM173 Small Molecules and Peptides" in 产品
STING/TMEM173 Small Molecules and Peptides
STING (stimulator of interferon genes) is encoded by the TMEM173 gene and is an adaptor molecule involved in the activation of innate immune responses to PAMPS (pathogen-associated molecular patterns) and DAMPS (damage-associated molecular patterns). STING specifically recognizes cytosolic DNA products derived from pathogens (e.g., cytomegalovirus, vaccinia virus, Listeria monocytogenes or dead cells (1, 2). In the STING pathway, dsDNA derived from pathogens or damaged cells serves as a ...
mSTING agonist; induces antitumor immunological responses
| Chemical Name: | 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid |
| Purity: | ≥98% |
Endogenous high affinity STING agonist
| Chemical Name: | 2',3'-Cyclic guanosine monophosphate-adenosine monophosphate sodium salt |
| Purity: | ≥98% |
Endogenous STING and DDX41 agonist; activates STING-dependent signaling
| Chemical Name: | 3',5'-Cyclic diguanylic acid sodium salt |
| Purity: | ≥98% |
Murine-selective STING agonist
| Chemical Name: | 9-Oxo-10(9H)-acridineacetic acid |
| Purity: | ≥98% |
Non-nucleotide STING agonist; orally bioavailable
| Chemical Name: | 4-(5,6-Dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid |
| Purity: | ≥98% |
STING agonist
| Chemical Name: | [P(R)]-5'-O-[(R)-Hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-adenosine cyclic nucleotide disodium |
| Purity: | ≥95% |
Pan-polymorph STING agonist
| Chemical Name: | 1-[(2-Chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-1H-indole-6-carboxamide |
| Purity: | ≥98% |
STING agonist, molecular glue that causes oligomerization of STING
| Chemical Name: | 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid |
| Purity: | ≥98% |
