4 results for "Synthetic Elastase Inhibitors" in 产品
Synthetic Elastase Inhibitors
Elastases are a group of serine proteases that specifically degrade elastin. Elastin, together with collagen, is a key protein that contributes to the mechanical properties of connective tissue.
There are two types of elastases; pancreatic elastase (E.C. 3.4.21.36) and leukocyte elastase (also known as neutrophil elastase) (E.C. 3.4.21.37). Pancreatic elastase is a digestive enzyme secreted from the pancreatic acinar cells and exists in a complex with α1-antitrypsin. Leukocyte elastase is a ...
Selective leukocyte elastase inhibitor
| Alternate Names: | ONO-5046 |
| Chemical Name: | N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium salt |
| Purity: | ≥98% |
Potent, orally active human leukocyte elastase inhibitor
| Chemical Name: | 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% |
High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active
| Chemical Name: | 5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide |
| Purity: | ≥98% |
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
| Chemical Name: | 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
| Purity: | ≥98% |
