TAS1R1 Proteins and Enzymes

FUNCTION: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.; SUBUNIT: Forms heterodimers with TAS1R3.; SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.; TISSUE SPECIFICITY: Expressed strongly only in fungiform papillae.