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TIMP-3: Products
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.
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"TIMP-3" has 34 results in Products.
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Proteome Profiler Human sReceptor Array, Non-hematopoietic
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Proteome Profiler Human Adipokine Array Kit
Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies
Proteome Profiler Human Protease/Protease Inhibitor Array
Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors
Proteome Profiler Human Protease Inhibitor Array Kit
Contains 4 membranes - each spotted in duplicate with 32 different protease inhibitor antibodies
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