TLE2 Proteins and Enzymes

TLE2 (transducin-like enhancer of split 2) also called ESG2 (enhancer of split groucho-like 2) is an 80 kDa (predicted) member of the WD repeat Groucho/TLE family of transcriptional repressors. It is a widely expressed transcriptional repressor that antagonizes transcription factors in the TCF (Wnt) signaling pathway. TLE2 forms homooligomers or he...