TMEM37 Proteins and Enzymes

The TMEM37 gene codes for a 190 amino acid long, 20 kDA transmembrane protein that is thought to stabilize the calcium channel in an inactivated state and monitors calcium current when coexpressed with CACNA1G. The TMEM37 gene is associated with food allergies, leukemia, and neuronitis and has been known to interact with genes HBP1, MPP3, ORM1, TNFRSF14, and TNFRSF11A. It plays a role in the MAPK signaling pathway.