TRAILR1/TNFRSF10A Proteins and Enzymes

TNF-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand and TNFSF10, is a type II transmembrane protein with a carboxy-terminal extracellular domain that exhibits homology to other TNF superfamily members.

TRAIL binds at least five different receptors: TRAILR1 (DR4), R2 (DR5), R3 (DcR1), R4 (DcR2), and osteoprotegerin (O...