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4 results for "TRPC Channel Activators" in 产品
TRPC Channel Activators
TRPC channels are complexes formed by four subunits, each with 6-transmembrane domains and several common features such as 3 or 4 ankyrin repeats in the N-terminal and a TRP box motif at proximal C-terminal. These cation channels are activated, to varying extents, by phospholipase C signaling pathway components, downstream of Gq/11 G protein-coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs). Activation of TRPC channels leads to cation influx, membrane depolarization and elevation ...
Potent and selective TRPC3/6 activator
| Chemical Name: | 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Purity: | ≥98% |
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Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
| Chemical Name: | 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid |
| Purity: | ≥98% |
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Selective positive allosteric modulator (PAM) of TRPC6
| Chemical Name: | 3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one |
| Purity: | ≥98% |
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Selective TRPC5 activator
| Chemical Name: | 6-Methyl-N-[3-(tricyclo[3.3.1.13,7]dec-1-yloxy)propyl]-4H-1,2,4-benzothiadiazine-3-propanamide-1,1-dioxide |
| Purity: | ≥98% |
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