UBE2V2 Proteins and Enzymes

Ubiquitin-conjugating Enzyme E2 Variant 2 (UBE2V2), also known as MMS2 and UEV2, is a 145 amino acid (aa) Ubiquitin-conjugating (E2) enzyme variant with a predicted molecular weight of approximately 16.5 kDa. The human protein shares 98% and 99% aa sequence identity with the mouse and rat orthologs, respectively. The E2 catalytic core domain of UBE2V2 lacks an active site cysteine residue, rendering it catalytically inactive. However, UBE2V2 can form a catalytically active complex with ...