Potent and selective 5-HT2C
values are 12 and 633 nM for 5-HT2C
receptors respectively). Displays high affinity for the 5-HT2B
= 38 nM) but acts as an inverse agonist. Active in vivo
; inhibits scratching in a mouse model of OCD.
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All Tocris products are intended for laboratory research use only.
SAR of psilocybin analogs: discovery of a selective 5-HT2C agonist.
Sard et al.