Chemical Name: 3-[2-(Dimethylamino)ethyl]-1-methylindol-4-ol
Biological Activity1-Methylpsilocin is a potent and selective 5-HT2C agonist (IC50 values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (Ki = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.
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SAR of psilocybin analogs: discovery of a selective 5-HT2C agonist.
Sard et al.
Citation for 1-Methylpsilocin
The citations listed below are publications that use Tocris products. Selected citations for 1-Methylpsilocin include:
1 Citation: Showing 1 - 1
Differential contributions of serotonin receptors to the behavioral effects of indoleamine hallucinogens in mice.
Authors: Halberstadt Et al.
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