(1R,1'S,3'R/1R,1'R,3'S)-L-054,264

Key Product Details

Product Description

(1R,1'S,3'R/1R,1'R,3'S)-L-054,264 is a potent and selective somatostatin sst₂ receptor agonist (K_i values are 4, 537, 2480, 3614 and 5017 nM for cloned human sst₂, sst₁, sst₄, sst₃ and sst₅ receptors respectively).

Product Specifications

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions

The following data is based on the product molecular weight 539.71.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.85 mL	9.26 mL	18.53 mL
5 mM	0.37 mL	1.85 mL	3.71 mL
10 mM	0.19 mL	0.93 mL	1.85 mL
50 mM	0.04 mL	0.19 mL	0.37 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Yang Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst₂) agonists. J.Med.Chem. 1998 PMID: 9632348

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