2-Methyl-5-hydroxytryptamine hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. 2-Substituted tryptamines: Agents with selectivity for 5-HT₆ serotonin receptors.
   Glennon et al.
   J.Med.Chem., 2000;43:1011
3. 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT₃ and putative 5-HT₄ receptors in guinea pig ileum.
   Craig et al.
   Naunyn Schmiedebergs Arch.Pharmacol., 1990;342:9
4. 5-HT₁ and 5-HT₂ binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin.
   Ismaiel et al.
   J.Med.Chem., 1990;33:755
5. 5-Hydroxytryptamine₃ receptors mediate tachycardia in conscious instrumented dogs.
   Wilson et al.
   J.Pharmacol.Exp.Ther., 1990;252:683

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