2-Methyl-5-hydroxytryptamine hydrochloride

Key Product Details

Product Description

5-HT₃ agonist (K_i = 1200 nM) and potent 5-HT₆ ligand (K_i = 46 nM).

Product Specifications for 2-Methyl-5-hydroxytryptamine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 2-Methyl-5-hydroxytryptamine hydrochloride

The following data is based on the product molecular weight 226.71.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

5 4 3 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.41 mL	22.05 mL	44.11 mL
5 mM	0.88 mL	4.41 mL	8.82 mL
10 mM	0.44 mL	2.21 mL	4.41 mL
50 mM	0.09 mL	0.44 mL	0.88 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Wilson 5-Hydroxytryptamine₃ receptors mediate tachycardia in conscious instrumented dogs. J.Pharmacol.Exp.Ther. 1990 PMID: 1968974
• Glennon 2-substituted tryptamines: agents with selectivity for 5-HT₆ serotonin receptors. J.Med.Chem. 2000 PMID: 10715164
• Ismaiel 5-HT₁ and 5-HT₂ binding profiles of the serotonergic agents α-methyl serotonin and 2-methylserotonin. J.Med.Chem. 1990 PMID: 2299641
• Craig 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT₃ and putative 5-HT₄ receptors in guinea pig ileum. Naunyn Schmiedebergs Arch.Pharmacol. 1990 PMID: 2402303

Product Documents for 2-Methyl-5-hydroxytryptamine hydrochloride