Catalog Number: 0620
Chemical Name: 4-Phenyl-1-(4-phenylbutyl)piperidine maleate
Biological Activity
σ ligand and selective non-competitive antagonist at recombinant NR1a/2B NMDA receptors expressed in Xenopus oocytes.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in ethanol and to 25 mM in DMSO
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel 1-phenylpiperazine and 4-phenylpiperidine derivatives as high affinity σ ligands.
    Glennon et al.
    J.Med.Chem., 1991;34:3360
  2. Antagonism of N-methyl-D-aspartate receptors by σ site ligands: potency, subtype-selectivity and mechanisms of inhibition.
    Whittemore et al.
    J.Pharmacol.Exp.Ther., 1997;282:326

The citations listed below are publications that use Tocris products. Selected citations for 4-PPBP maleate include:

Showing Results 1 - 1 of 1

  1. σ receptor agonists provide neuroprotection in vitro by preserving bcl-2.
    Authors: Yang Et al.
    Front Behav Neurosci
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