6-Iodonordihydrocapsaicin
Purity: ≥99%
Biological Activity
Potent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC50 = 10 nM). Inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists.
Appendino et al.
Br.J.Pharmacol., 2003;139:1417
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Citation for 6-Iodonordihydrocapsaicin
The citations listed below are publications that use Tocris products. Selected citations for 6-Iodonordihydrocapsaicin include:
1 Citation: Showing 1 - 1
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Effects of luminal thymol on epithelial transport in human and rat colon.
Authors: Kaji Et al.
Am J Physiol Gastrointest Liver Physiol 2011;300:G1132
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