6-Iodonordihydrocapsaicin

Key Product Details

Product Description

Potent competitive vanilloid TRPV1 (VR1) receptor antagonist (IC₅₀ = 10 nM). Inhibits capsaicin-induced [Ca²⁺]_i increase in rat DRG neurons, and guinea pig bladder and trachea contractions in vitro.

Product Specifications for 6-Iodonordihydrocapsaicin

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for 6-Iodonordihydrocapsaicin

The following data is based on the product molecular weight 419.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.38 mL	11.92 mL	23.85 mL
5 mM	0.48 mL	2.38 mL	4.77 mL
10 mM	0.24 mL	1.19 mL	2.38 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 264 publications citing the usage of this product.

• Appendino Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists. Br.J.Pharmacol. 2003 PMID: 12922928

Product Documents for 6-Iodonordihydrocapsaicin