6-Thioguanine

Catalog # Availability Size / Price Qty
4061/50
Immunosuppressants Small Molecule
1 Image
Description: Anticancer and immunosuppressive agent
Alternative Names: 6-TG

Chemical Name: 2-Amino-6-mercaptopurine

Purity: ≥99%

Product Details
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Biological Activity

Anticancer and immunosuppressive agent often used to treat immune disorders and leukemia. Displays cytotoxic and antineoplastic properties; disrupts cytosine methylation by DNA methyltransferases after incorporation into DNA. Selectively kills BRCA2-defective tumors in a xenograft model. Also facilitates proteasome-mediated degradation of DNA (cytosine-5)-methyltransferase 1 (DNMT1).

Technical Data

M.Wt:
167.19
Formula:
C5H5N5S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
154-42-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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⚠ WARNING: This product can expose you to chemicals including Thioguanine, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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