6,2',4'-Trimethoxyflavone
Chemical Name: 2',4',6-Trimethoxyflavone
Purity: ≥97%
Biological Activity
Aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
Murray et al.
J.Pharmacol.Exp.Ther., 2010;332:135
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Citation for 6,2',4'-Trimethoxyflavone
The citations listed below are publications that use Tocris products. Selected citations for 6,2',4'-Trimethoxyflavone include:
1 Citation: Showing 1 - 1
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Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens.
Authors: Gimenez-Gomez Et al.
Neuropharmacology 2018;135:581
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Purchased to independently test published results and was successful. Compound purity was as described. Happy with purchase