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6,2',4'-Trimethoxyflavone

3859 1 Citation 1 Review Datasheet / COA / SDS

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6,2',4'-Trimethoxyflavone | CAS No. 720675-74-1 | Aryl Hydrocarbon Receptor Antagonists
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Description: Aryl hydrocarbon receptor antagonist

Chemical Name: 2',4',6-Trimethoxyflavone

Purity: ≥97%

Product Details
Citations (1)
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

6,2',4'-Trimethoxyflavone is an aryl hydrocarbon receptor antagonist (EC50 = 0.9 μM). Exhibits no short term agonist activity and no species or promoter dependence.

Technical Data

M.Wt:
312.32
Formula:
C18H16O5
Solubility:
Soluble to 5 mM in DMSO with gentle warming
Purity:
≥97%
Storage:
Store at RT
CAS No:
720675-74-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone.
    Murray et al.
    J.Pharmacol.Exp.Ther., 2010;332:135

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Citation for 6,2',4'-Trimethoxyflavone

The citations listed below are publications that use Tocris products. Selected citations for 6,2',4'-Trimethoxyflavone include:

1 Citation: Showing 1 - 1

  1. Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens.
    Authors: Gimenez-Gomez Et al.
    Neuropharmacology  2018;135:581

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Reviews for 6,2',4'-Trimethoxyflavone

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Good choice
By Anonymous on 08/20/2018
Application: Species: Human

Purchased to independently test published results and was successful. Compound purity was as described. Happy with purchase

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