Home / Guanylyl Cyclase Activators / A 350619 hydrochloride

A 350619 hydrochloride

2753 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2753/10
2753/50
A 350619 hydrochloride | CAS No. 1217201-17-6 | Guanylyl Cyclase Activators
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Description: Soluble guanylyl cyclase (sGC) activator

Chemical Name: 3-[2-[(4-Chlorophenyl)thiophenyl]-N-[4-(dimethylamino)butyl]-2-propenamide hydrochloride

Purity: ≥99%

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Biological Activity

Activator of soluble guanylyl cyclase (sGC). Activates basal sGC and synergistically activates sGC in the presence of NO. Relaxes cavernosum smooth muscle in vitro and induces penile erections in rats. Induces a sustained increase in skin blood flow in vivo.

Technical Data

M.Wt:
425.41
Formula:
C21H25ClN2OS.HCl
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
1217201-17-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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