A 943931 dihydrochloride

Catalog # Availability Size / Price Qty
3753/10
3753/50
A 943931 dihydrochloride | CAS No. 1227675-50-4 | Histamine H4 Receptor Antagonists
1 Image
Description: Potent and selective H4 antagonist

Chemical Name: 4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine

Purity: ≥98%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

Potent and selective histamine H4 receptor antagonist (pKi values are 7.15 and 8.12 at human and rat receptors respectively). Blocks inflammation in a peritonitis mouse model and displays efficacy in inflammatory pain and neuropathic pain models.

Technical Data

M.Wt:
368.31
Formula:
C17H21N5.2HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Desiccate at RT
CAS No:
1227675-50-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for A 943931 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for A 943931 dihydrochloride include:

1 Citation: Showing 1 - 1

  1. Mast Cells in the Developing Brain Determine Adult Sexual Behavior.
    Authors: Lenz Et al.
    J Neurosci  2018;38:8044

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for A 943931 dihydrochloride

There are currently no reviews for this product. Be the first to review A 943931 dihydrochloride and earn rewards!

Have you used A 943931 dihydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.