A 943931 dihydrochloride

Discontinued Product

3753 has been discontinued.
View all Histamine H4 Receptor Antagonists products.
A 943931 dihydrochloride | CAS No. 1227675-50-4 | Histamine H4 Receptor Antagonists
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Description: Potent and selective H4 antagonist

Chemical Name: 4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine

Purity: ≥98%

Product Details
Citations (1)

Biological Activity

A 943931 dihydrochloride is a potent and selective histamine H4 receptor antagonist (pKi values are 7.15 and 8.12 at human and rat receptors respectively). Blocks inflammation in a peritonitis mouse model and displays efficacy in inflammatory pain and neuropathic pain models.

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for A 943931 dihydrochloride

The citations listed below are publications that use Tocris products. Selected citations for A 943931 dihydrochloride include:

1 Citation: Showing 1 - 1

  1. Mast Cells in the Developing Brain Determine Adult Sexual Behavior.
    Authors: Lenz Et al.
    J Neurosci  2018;38:8044


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