Adenosine 5'-(α,β-methylene)diphosphate sodium salt

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Adenosine 5'-(α,β-methylene)diphosphate sodium salt | CAS No. 89016-30-8 | NTPDase Inhibitors
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Description: Ecto-5'-nucleotidase (CD73) inhibitor
Alternative Names: AMPCP, APCP

Chemical Name: α,β-Methyleneadenosine 5'-diphosphate monosodium salt

Purity: ≥98%

Product Details
Citations (2)

Biological Activity

Adenosine 5'-(α,β-methylene)diphosphate sodium salt is an Ecto-5'-nucleotidase/CD73 inhibitor. Blocks ecto-5'-nucleotidase-mediated adenosine production by preventing the conversion of AMP to adenosine. Reverses the doxorubicin-resistance in ecto-5'-nucleotidase-positive MDR cells (MCF7/A6 and L1210/A). Also increases rhodamine uptake and inhibits rhodamine efflux from ecto-5'-nucleotidase-positive MDR cells. Vasoconstrictor.

Technical Data

Soluble in water (supplied pre-dissolved at a concentration of 10mM)
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Adenosine 5'-(α,β-methylene)diphosphate sodium salt

The citations listed below are publications that use Tocris products. Selected citations for Adenosine 5'-(α,β-methylene)diphosphate sodium salt include:

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