Alfuzosin hydrochloride

Catalog # Availability Size / Price Qty
3305/10
3305/50
Alfuzosin hydrochloride | CAS No. 81403-68-1 | Adrenergic alpha-1 Receptor Antagonists
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Description: Uroselective α1 antagonist

Chemical Name: N-[3-[(4-Amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride

Purity: ≥99%

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Biological Activity

Functionally uro-selective α1 adrenoceptor antagonist that does not discriminate between α1 subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC50 = 7.64) in vitro.

Technical Data

M.Wt:
425.91
Formula:
C19H27N5O4.HCl
Solubility:
Soluble to 25 mM in water and to 25 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
81403-68-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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