Catalog Number: 1562
Alternate Names: [Ile5]Angiotensin I (1-7), Ang-(1-7)
Biological Activity
Endogenous peptide fragment. Induces vasorelaxation through release of NO and prostaglandins, perhaps through activation of a non-AT1, non-AT2 receptor, Mas. Counteracts the vasoconstrictive and proliferative effects of angiotensin II and stimulates vasopressin (anti-diuretic hormone) release in vivo.
Technical Data
  • M.Wt:
    899
  • Formula:
    C41H62N12O11
  • Sequence:
    DRVYIHP
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    51833-78-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Angiotensin-(1-7) is involved in the endothelium-dependent modulation of phenylephrine-induced contraction in the aorta of mRen-2 transgenic rats.
    Lemos et al.
    Br.J.Pharmacol., 2002;135:1743
  2. Angiotensin-(1-7): an update.
    Santos et al.
    Regul.Pept., 2000;91:45
  3. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas.
    Santos et al.
    Proc.Natl.Acad.Sci.U.S.A., 2003;100:8258

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